Ryanair has introduced six new routes from Manchester Airport to Bratislava, Bremen, Brindisi, Carcassonne, Limoges and Malta.
Announcing its Manchester Summer 2016, the airline has also added flights to its existing ten routes.
As Ryanair grows by 25% at Manchester, it serves 500,000 new customers leading to 3.8 million customers in total, and supports 2,800 jobs.
Ryanair chief marketing officer Kenny Jacobs said: "Manchester is one of the fastest growing airports in the Ryanair network, and we look forward to working closely with Manchester Airport Group as we continue to grow jobs, traffic and routes in the North West.
"To celebrate the launch of our Manchester Summer 2016 schedule, we are releasing 100,000 seats for sale across our European network at fares starting from just £19.99."
The people commuting to and from the UK will be able to make a choice from Ryanair's 41 low fare Manchester routes and can also enjoy facilities such as new bases, a new personalised website, new app, new cabin interiors, new crew uniforms and improved inflight menus.
The summer 2016 schedule will also deliver one additional based aircraft, and 250 weekly flights.
Manchester Airport managing director Ken O'Toole said: "With new routes for the airport and further capacity increases on existing services, today's announcement will provide passengers with more choice and value, and will contribute to further sustained growth by Manchester Airport beyond our current all-time passenger record of 22.9m passengers.
"With over 22 million people living within our two hour catchment, two full length runways and a £1bn transformation programme announced, Manchester Airport has, and will continue to have, the available capacity and demand to meet the needs of our catchment that extends as far North as Scotland and South to the Midlands."
The Manchester schedule was released days after Ryanair announced the Birmingham Summer Schedule 2016.
Two new routes will be operated from Birmingham to Corfu and Vilnius, increasing the total routes to 21 and delivering 1.75 million passengers annually.
Earlier this month, the airline announced that it will open a base at Corfu in April 2016, with one based aircraft, 11 new routes to Birmingham, Bratislava, Budapest, Cologne, Rome, Katowice, Poznan, Pisa, Rzeszow, Venice and Warsaw.
Image: Manchester is one of the fastest growing airports in the Ryanair network. Photo: courtesy of Ryanair.